2203 citations with an h-index of 23, i10-index of 31.
Google Scholar link:



[3] Y.-S. Chen, S. S. Gambhir, “Molecular imaging agent based on encapsulated saline for radio frequency molecular imaging”, US-2020-0323999-A1, (2020).

[2] S. Emelianov, J. Su, B. Wang, A. Karpiouk, Y.-S. Chen, W. Frey, R. Bouchard, “Combined ultrasound and photoacoustic imaging of metal objects”, U.S. Patent 20,120,253,180, (2012).

[1] P1. S. Emelianov, B. Wang, J. Shah, K. Sokolov, J. Su, Y.-S. Chen, W. Frey, “Temperature dependent photoacoustic imaging”, U.S. Patent 20120125107 A1, (2012).



[1] Y.-S. Chen, and S. Emelianov*, “Photoacoustic imaging of cancer therapy” in Cancer Theranostics, Chapter 9, X. Chen ed., Elsevier, US, ISBN: 978-0-12-407722-5, (2014).



[33] H. Wang, H.-K. Huang, Y.-S. Chen*, and Y. Zhao*, “On-demand field shaping for enhanced magnetic resonance imaging using an ultrathin reconfigurable metasurface”, VIEW, 2021. DOI: 10.1002/VIW.20200099 

[32] Y.-S. Chen*, Y. Zhao, C. Beinat, A. Zlitni, E.-C. Hsu, D.-H. Chen, H. Wang, T. Stoyanova, J. A. Dionne, and S. S. Gambhir, “Ultra-high-frequency-radio-frequency-acoustic molecular imaging with saline nanodroplets in living subjects”, Nature Nanotechnology, 2021. DOI: 10.1038/s41565-021-00869-5

[31] Cui, A. Gouw, Y. Tang, J. Qi, E. LaGory, Y.-S. Chen, Z. Gao, M. Chen, L. Hu, J. Xie, Q. Zhu, Z. Wang, A. J. Giaccia, S. S. Gambhir, W. Zhu, D. Felsher, M. Pegram, J. Rao*, “Mitochondrial copper depletion suppresses triple-negative breast cancer in mice”, Nature Biotechnology, 2020. DOI: 10.1038/s41587-020-0707-9

[30] G. Song, M. Kenney, Y.-S. Chen, X. Zheng, Y. Deng, S. X. Wang, S. S. Gambhir, H. Dai, J. Rao*, “Iron-cobalt Nanoalloy for Magnetic Particle Imaging and Photo/Magneto Hyperthermia Cancer Therapy”, Nature Bioengineering, 2020, 4, 325. DOI: 10.1038/s41551-019-0506-0.

[29] E.-C. Hsu, M. A. Rice, A. Bermudez, F. J. G. Marques, M. Aslan, A. Ghoochani, C. A. Zhang, Y.-S. Chen, A. Zlitni, F. Habte, S. Kumar, R. Nolley, D. M. Peehl, A. Zoubeidi, S. S. Gambhir, C. Kunder, S. Pitteri, J. D. Brooks, T. Stoyanova*, “Trop2 is a Driver of Metastatic Castration Resistant Prostate Cancer with Neuroendocrine Phenotype via PARP1”, Proceedings of the National Academy of Sciences of the United States of America (PNAS), 2020, 117, 2032. DOI: 10.1073/pnas.1905384117

[28] N. Jahana, H. Wang, S. Zhao, A. Dutta, H.-K. Huang, Y. Zhao, Y.-S. Chen, “Optical force microscopy: combining light with atomic force microscopy for nanomaterial identification”, Nanophotonics, 2019, 8(10), 1659–1671. DOI: 10.1515/nanoph-2019-0181

[27] K. Shahbazi, W. Frey, Y.-S. Chen, S. Aglyamov, and S. Emelianov, “Photoacoustics of core-shell nanospheres: signal composition and the role of interfacial conductance and laser pulse waveform”, Nature Publishing Group: Communications Physics, 2019, 2, 119. DOI: 10.1038/s42005-019-0216-7

[26] Y.-S. Chen, Y. Zhao, S. Yoon, S. Emelianov, S. S. Gambhir, “Miniature gold nanorods for photoacoustic molecular imaging in the second near-infrared optical window”, Nature Nanotechnology, 2019, 14, 465–472. DOI: 10.1038/s41565-019-0392-3

[25] C. Beinat, T. Haywood, Y.-S. Chen, I. S Alam, S. Murty, S. S. Gambhir, “The utility of [18F]DASA-23 for molecular imaging of prostate cancer with positron emission tomography”, Molecular Imaging and Biology, 2018, 20(6), 1015.  DOI: 10.1007/s11307-018-1194-y

[24] Y.-S. Chen, S. Yoon, W. Frey, M. Dockery, S. Emelianov, “Dynamic contrast-enhanced photoacoustic imaging using photothermal stimuli-responsive composite nanoamplifiers”, Nature Communications, 2017, 8, 15782. DOI:10.1038/ncomms15782

[23] A. S. Hannah, D. VanderLaan, Y.-S. Chen, D. Yeager, S Emelianov, “Photoacoustic and ultrasound ex vivo imaging using dual contrast perfluorocarbon nanodroplets triggered by laser pulses at 1064 nm”, Biomedical Optics Express, 2014, 5(9), 3042. DOI: 10.1364/BOE.5.003042

[22] D. Yeager, Y.-S. Chen, S. Litovsky, and S. Emelianov, “Intravascular photoacoustics for imaging-guided plasmonic photothermal therapy of atherosclerotic plaques”, Theranostics, 2014, 4(1), 36–46. DOI:10.7150/thno.7143

[21] J. Luke, A. Bashyam, K. Homan, S. Makhija, Y.-S. Chen, and S. Emelianov, “Silica-coated gold nanoplates as stable photoacoustic contrast agents for longitudinal sentinel lymph node imaging”, Nanotechnology, 2013, 24, 455101. DOI:10.1088/0957-4484/24/45/455101

[20] S. Kim, Y.-S. Chen, G. P. Luke, and S. Emelianov, “Ultrasound and photoacoustic image-guided photothermal cancer therapy: in-vivo study using silica-coated gold nanorods”, IEEE Transactions on UFFC, 2014, 61(5), 891. DOI: 10.1109/TUFFC.2014.6805702

[19] Y.-S. Chen, W. Frey, S. Aglyamov, C. Walker, and S. Emelianov, “Sensitivity enhanced nanothermal sensors for photoacoustic temperature mapping”, Journal of Biophotonics, 2013, 6(6-7), 534-542. DOI: 10.1002/jbio.201200219 Cover Article

[18] P. Joshi, S. Yoon, Y.-S. Chen, S. Emelianov, and K. V. Sokolov, “Development and optimization of near-IR contrast agents for immune cell tracking”, Biomedical Optics Express, 2013, 6(6-7), 534-542. DOI: 10.1364/BOE.4.002609

[17] D. Yeager, Y.-S. Chen, S. Litovsky, S. Emelianov, “TCT-637 Intravascular ultrasound and photoacoustic imaging of plasmonic nanoparticles for combined diagnosis and image-guided therapy of atherosclerotic plaques”, Journal of the American College of Cardiology, 2013, 62 (18_S1), B194-B194. DOI: 10.1016/j.jacc.2013.08.1386

[16] T. Mitcham, K. Homan, W. Frey, Y.-S. Chen, S. Emelianov, J. Hazle, and R. Bouchard, “Modulation of photoacoustic signal generation from metallic surfaces”, Journal of Biomedical Optics, 2013, 18 (5), 056008. DOI:10.1117/1.JBO.18.5.056008

[15] C. Bayer, S. Nam, Y.-S. Chen, and S. Emelianov, “Photoacoustic signal amplification through plasmonic nanoparticle aggregation”, Journal of Biomedical Optics, 2013, 18(1), 016001. DOI:10.1117/1.JBO.18.1.016001

[14] Y.-S. Chen, W. Frey, S. Aglyamov, and S. Emelianov, “Environment-dependent generation of photoacoustic waves from plasmonic nanoparticles”, Small, 2012, 8, 47-52. DOI: 10.1002/smll.201101140

[13] Y.-S. Chen, W. Frey, S. Kim, P. Kruizinga, K. Homan, and S. Emelianov, “Silica-coated gold nanorods as photoacoustic signal nano-amplifiers”, Nano Letters, 2011, 11(2), 348-354.  DOI: 10.1021/nl1042006

[12] C. Bayer, Y.-S. Chen, S. Kim, S. Mallidi, K. Sokolov, and S. Emelianov, “Multiplex photoacoustic molecular imaging using targeted silica-coated gold nanorods”, Biomedical Optics Express, 2011, 2(7), 1828-1835.  DOI: 10.1364/BOE.2.001828

[11] S. Kim, Y.-S. Chen, G. P. Luke, and S. Emelianov, “In vivo three-dimensional spectroscopic photoacoustic imaging for monitoring nanoparticle delivery”, Biomedical Optics Express, 2011, 2(9), 2540-2550. DOI: 10.1364/BOE.2.002540

[10] M. Qu, S. Mallidi, M. Mehrmohammadi, R. Truby, K. Homan, P. Joshi, Y.-S. Chen, K. Sokolov, and S. Emelianov,    “Magneto-photoacoustic imaging”, Biomedical Optics Express, 2011, 2(2), 385–395. DOI: 10.1364/BOE.2.000385

[9]  Y.-S. Chen, W. Frey, S. Kim, K. Homan, P. Kruizinga, K. Sokolov, S. Emelianov, “Enhanced thermal stability of silica-coated gold nanorods for photoacoustic imaging and image-guided therapy”, Optics Express, 2010, 18(9), 8867-8878. DOI: 10.1364/OE.18.008867

[8]  K. Homan, S. Kim, Y.-S. Chen, B. Wang, S. Mallidi, and S. Emelianov, “Prospects of molecular photoacoustic imaging at 1064 nm wavelength”, Optics Letters, 2010, 35(15), 2663-2665.  DOI: 10.1364/OL.35.002663

[7]  L. Su, B. Wang, K. E. Wilson, C. Bayer, Y.-S. Chen, S. Kim, K. A Homan, and S. Emelianov, “Advances in clinical and biomedical applications of photoacoustic imaging”, Expert Opinion on Medical Diagnostics, 2010, 4(6), 497-510. DOI: 10.1517/17530059.2010.529127

[6]  Y.-S. Chen, Y. Zhao, A. Hosseini, D. Kwong, R. T. Chen, “Delay time enhanced flat band photonic crystal waveguides with capsule-shaped holes on silicon nanomembrane”, IEEE Journal of Selected Topics in Quantum Electronics, 2009, 15(5), 1510-1514. DOI: 10.1109/JSTQE.2009.2020811

[5]  X. Chen, Y.-S. Chen, Y. Zhao, W. Jiang, R. T. Chen, “0.54 pJ/bit Capacitor-embedded silicon slot photonic crystal waveguide modulator”, Optics Letters, 2009, 34(5), 602-604. DOI: 10.1364/OL.34.000602

[4]  A. Hosseini, D. Kwong, Y. Zhao, Y.-S. Chen, F. Crnogorac, R. F. W. Pease, and R. T. Chen, “Unequally-spaced waveguide arrays for silicon nano membrane-based efficient large-angle optical beam steering”, IEEE Journal of Selected Topics in Quantum Electronics, 2009, 15(5), 1439-1446. DOI: 10.1109/JSTQE.2009.2021956

[3]  Y.-S. Chen, A. Tal, and S. M. Kuebler, “Route to three-dimensional metallized microstructures using cross linkable epoxide SU-8”, Chemistry of Materials, 2007, 19(16), 3858-3860. DOI: 10.1021/cm0710812

[2]  A. Tal, Y.-S. Chen, H. E. Williams, R. C. Rumpf, S. M. Kuebler, “Fabrication and characterization of three-dimensional copper metallodielectric photonic crystals”, Optics Express, 2007, 15(26), 18283-18293. DOI: 10.1364/OE.15.018283

[1]  Y.-S. Chen, A. Tal, D. B. Torrance, S. M. Kuebler, “Fabrication and characterization of three-dimensional silver-coated polymeric microstructures”, Advanced Functional Materials, 2006, 16(13), 1739-1744. DOI: 10.1002/adfm.200600394